Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line
Mohammad Jahidul Islam, Sidratul Muntaha, Md Mohiuddin Masum, Sazia Nowshin, Sabia Salam, Mominul Haque, Myo Wint Zaw, Shahriar Jahan · 2024
Read Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line by Mohammad Jahidul Islam, Sidratul Muntaha, Md Mohiuddin Masum, Sazia Nowshin, Sabia Salam, Mominul Haque, Myo Wint Zaw, Shahriar Jahan (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12008332.txt.
Description
Myo-inositol, a sugar-like compound found in many foods, may fight prostate cancer. Mohammad Jahidul Islam and co-authors tested in 2024 its effect on a prostate cancer cell line grown in the lab.
The compound cut cell survival sharply at modest doses. Protein profiling then compared treated and untreated cells. Treatment suppressed some structural proteins and raised others tied to cell death pathways and tumor suppression, including factors in stress response. The pattern suggests the compound tilts the cell's machinery toward dying rather than growing. The authors call it a promising add-on candidate, while noting combination therapy studies must come next.
Catalog record
| CREATOR | Mohammad Jahidul Islam, Sidratul Muntaha, Md Mohiuddin Masum, Sazia Nowshin, Sabia Salam, Mominul Haque, Myo Wint Zaw, Shahriar Jahan |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |