治疗前外周血血红蛋白×淋巴细胞/单核细胞水平对鼻咽癌患者预后的影响
Chao DENG, Zui CHEN, Jie LING, Yangchun XIE, Xiayan ZHAO, Chunhong HU, Xianling LIU, Yuhua FENG, Tao HOU, 敏宁 彭 · 2024
Read 治疗前外周血血红蛋白×淋巴细胞/单核细胞水平对鼻咽癌患者预后的影响 by Chao DENG, Zui CHEN, Jie LING, Yangchun XIE, Xiayan ZHAO, Chunhong HU, Xianling LIU, Yuhua FENG, Tao HOU, 敏宁 彭 (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11975518.txt.
Description
A simple ratio computed from a routine blood test may help predict survival after treatment for nasopharyngeal carcinoma, a cancer of the upper throat. Chao Deng and co-authors reviewed 805 patients who had received definitive radiotherapy, with or without chemotherapy. For each one they calculated HLMR: hemoglobin multiplied by the ratio of lymphocytes to monocytes, two white cell types. A cutoff near 605 split patients into high and low groups.
High HLMR independently predicted better overall and progression-free survival, alongside tumor stage and treatment type. The team folded HLMR into a nomogram that estimated three-, five-, and seven-year survival with fair accuracy, and the chart held up in a validation group. The authors propose the cheap, pretreatment blood measure as a practical outcome marker for this cancer.
Catalog record
| CREATOR | Chao DENG, Zui CHEN, Jie LING, Yangchun XIE, Xiayan ZHAO, Chunhong HU, Xianling LIU, Yuhua FENG, Tao HOU, 敏宁 彭 |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |