Effect analysis of entecavir on serum hyaluronic acid, laminin and IV collagen in the treatment of hepatitis B E-antigen-positive chronic hepatitis B
Jiancheng Qian, Xiaoyong Sun, Yue Cheng · 2024
Read Effect analysis of entecavir on serum hyaluronic acid, laminin and IV collagen in the treatment of hepatitis B E-antigen-positive chronic hepatitis B by Jiancheng Qian, Xiaoyong Sun, Yue Cheng (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11970162.txt.
Description
Scarring of the liver can be tracked in the blood through three markers: hyaluronic acid, laminin, and type IV collagen. The authors study patients with hepatitis B whose virus carries the e-antigen, comparing entecavir alone against entecavir plus thymalfasin, an immune booster. Liver enzymes, immune cell counts, and the three scarring markers are measured before and after treatment in both groups. Before treatment, the groups look the same on every measure.
After treatment, the combination group shows lower bilirubin and liver enzyme levels, stronger immune indicators, and lower levels of all three scarring markers. The differences reach statistical significance. The authors conclude that entecavir works well on its own for this form of hepatitis B. Adding thymalfasin, they argue, eases symptoms further, helps hold back liver fibrosis, and strengthens the overall clinical effect. They present the pairing as the better option for these patients.
Catalog record
| CREATOR | Jiancheng Qian, Xiaoyong Sun, Yue Cheng |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 16 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |