A case of toxoplasmic encephalitis in a patient on cancer chemotherapy in Uganda
Yekosani Mitala, Raymond Atwine, Abraham Birungi, Ambaru Jacinta, Kuraishi Baluku, Semei Sekitene, Edwin Nuwagira · 2024
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Description
Yekosani Mitala and co-authors report a brain infection case in a cancer patient in Uganda in a paper published in 2024. The patient, a 46-year-old man with well-controlled HIV, began having seizures after his second round of chemotherapy for food pipe cancer. Scans showed swollen brain chambers but no tumor-like mass.
Fluid drawn from around the brain held the parasite that causes toxoplasmosis, in both its resting and active forms. The infection had reawakened because chemo and HIV together had weakened his immune defenses. Such reactivation is known in HIV care but took an unusual, deadly form here. The authors warn clinics in low-income countries, where cancer and HIV often overlap, to watch for this hidden cause.
Catalog record
| CREATOR | Yekosani Mitala, Raymond Atwine, Abraham Birungi, Ambaru Jacinta, Kuraishi Baluku, Semei Sekitene, Edwin Nuwagira |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 13 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |