Expression of cyclooxygenase-2 (COX-2) in colorectal carcinoma in an indigenous African population of Kano, Nigeria
Jimoh Ajanaku Abdulrazaq, Mohammed Aminu Zakari, Yusuf Ibrahim, Hamza Ahmad · 2024
Read Expression of cyclooxygenase-2 (COX-2) in colorectal carcinoma in an indigenous African population of Kano, Nigeria by Jimoh Ajanaku Abdulrazaq, Mohammed Aminu Zakari, Yusuf Ibrahim, Hamza Ahmad (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11959126.txt.
Description
Jimoh Abdulrazaq and co-authors measure a cancer-linked enzyme in bowel tumors from patients in Kano, Nigeria. Their 2024 study stains 124 tumor samples for COX-2, an enzyme often overproduced in colorectal cancer. African data on this marker are scarce, even as bowel cancer rises there and strikes younger patients.
Nearly half the tumors overproduced the enzyme. Cases clustered in middle age, with over half arising before age fifty, and men outnumbered women two to one. Strong expression tied closely to the common adenocarcinoma type, especially its less differentiated forms. It did not track with age or sex. The authors say the marker may shape outcomes and could guide targeted therapy or prevention work.
Catalog record
| CREATOR | Jimoh Ajanaku Abdulrazaq, Mohammed Aminu Zakari, Yusuf Ibrahim, Hamza Ahmad |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |