Peripheral Endothelial Dysfunction Is Associated With Incident Major Depressive Disorder

Jaskanwal D S Sara, Nazanin Rajai, Scott Breitinger, Betsy Medina‐Inojosa, Lilach O Lerman, Francisco Lopez‐Jimenez, Amir Lerman · 2024

Read Peripheral Endothelial Dysfunction Is Associated With Incident Major Depressive Disorder by Jaskanwal D S Sara, Nazanin Rajai, Scott Breitinger, Betsy Medina‐Inojosa, Lilach O Lerman, Francisco Lopez‐Jimenez, Amir Lerman (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11935717.txt.

Description

Jaskanwal Sara and six co-authors test whether poor blood vessel function in the limbs foretells a later diagnosis of major depression. A finger-based test measured how well small vessels relax after a squeeze, in 1,614 patients having heart risk checks. Records were then searched for formal depression evaluations in the years after the test. About thirty percent of the group took such an evaluation, and roughly a third of those received the diagnosis.

Patients later diagnosed with depression had shown the vessel problem more often at baseline, forty percent against thirty. After statistical adjustment, the vessel problem more than doubled the odds of a later depression diagnosis. The authors suggest the simple finger test could flag people who deserve closer mood watching and earlier care. The finding fits a wider story linking vessel health to the depressed brain.

Catalog record

CREATORJaskanwal D S Sara, Nazanin Rajai, Scott Breitinger, Betsy Medina‐Inojosa, Lilach O Lerman, Francisco Lopez‐Jimenez, Amir Lerman
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE31 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11935717

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