The Pathologic Roles and Therapeutic Implications of Ghrelin/GHSR System in Mental Disorders
Qianshuo Mao, Jinjia Wang, Zihan Yang, Ruidong Ding, Shuangyu Lv, Xinying Ji · 2024
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Description
Qianshuo Mao and co-authors review the hunger hormone ghrelin and its role in mental disorders in a 2024 paper. Ghrelin is a twenty-eight amino acid hormone, and its receptor is found in the brain, pituitary, and adrenal glands, above all in the hypothalamus. Through that receptor, ghrelin shapes many of its biological effects.
Ghrelin is closely tied to the onset of psychosis. It can influence dopamine, GABA, and serotonin signaling through the hormone axis linking brain and adrenals. The review covers both the harmful roles of this system in mental illness and what blocking or tuning it might offer as therapy.
Catalog record
| CREATOR | Qianshuo Mao, Jinjia Wang, Zihan Yang, Ruidong Ding, Shuangyu Lv, Xinying Ji |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |