Rapid Point-of-care Testing to Inform Intrapartum Treatment of Group B Streptococcus–Colonized Women in Uganda
Juliet Nsimire Sendagala, Melanie Etti, Rose Azuba, Joseph Peacock, Kirsty Le Doare, PROGRESS Study Author Group · 2025
Read Rapid Point-of-care Testing to Inform Intrapartum Treatment of Group B Streptococcus–Colonized Women in Uganda by Juliet Nsimire Sendagala, Melanie Etti, Rose Azuba, Joseph Peacock, Kirsty Le Doare, PROGRESS Study Author Group (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11891131.txt.
Description
Juliet Nsimire Sendagala and co-authors evaluate, in a 2024 study from Uganda, a rapid test for a germ that can kill newborns. Group B Streptococcus often lives quietly in mothers, but it can cause severe disease in babies. Finding it in time to give antibiotics during labour usually needs lab culture, which is scarce in low-resource settings.
The team tested a fast gene-based method on rectal and vaginal swabs. In the main phase, swabs from 1,294 pregnant women were enriched in broth, then tested by the rapid method and by culture side by side. The rapid test found far more positives than culture did. A tie-breaker gene test agreed with the rapid result in over ninety-six percent of disputed cases. Accuracy after adjustment was high on both sensitivity and specificity.
Catalog record
| CREATOR | Juliet Nsimire Sendagala, Melanie Etti, Rose Azuba, Joseph Peacock, Kirsty Le Doare, PROGRESS Study Author Group |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |