Microbiome structure in healthy and pregnant women and importance of vaginal dysbiosis in spontaneous abortion

Majid Eslami, Ramtin Naderian, Ariyan Ahmadpour, Ali Shushtari, Sahar Maleki, Parham Mohammadian, Arvin Amiri, Maryam Janbazi, Mohammad Memarian, Bahman Yousefi · 2025

Read Microbiome structure in healthy and pregnant women and importance of vaginal dysbiosis in spontaneous abortion by Majid Eslami, Ramtin Naderian, Ariyan Ahmadpour, Ali Shushtari, Sahar Maleki, Parham Mohammadian, Arvin Amiri, Maryam Janbazi, Mohammad Memarian, Bahman Yousefi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11881085.txt.

Description

Majid Eslami and co-authors published a review, with the head dated 2024, on the vaginal microbiome in healthy and pregnant women and its link to miscarriage. In healthy women, lactobacillus species dominate this community. Imbalance is tied to infections, failed implantation, and early birth. Pregnancy shifts the community toward a simpler lactobacillus-led state with lower metabolic range.

Many factors shape the community, from age and hormones to smoking, diet, and the menstrual cycle. Loss of the community early in pregnancy raises miscarriage risk, though high diversity alone does not always cause loss. Lactobacillus guards against pathogens with acid and other compounds. The review sorts the main forces that keep or break balance.

Catalog record

CREATORMajid Eslami, Ramtin Naderian, Ariyan Ahmadpour, Ali Shushtari, Sahar Maleki, Parham Mohammadian, Arvin Amiri, Maryam Janbazi, Mohammad Memarian, Bahman Yousefi
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE45 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11881085

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