Lurasidone uses and dosages in Spain: RETROLUR, a real-world retrospective analysis using artificial intelligence
Fernando Mora, Carlos Gómez Sánchez-Lafuente, Mariano De Iceta, Carolina Roset, Antonio Cárdenas, Daniel Pérez, Elena Álvarez-Barón, Irene Gabarda-Inat, Savana Research Group · 2025
Read Lurasidone uses and dosages in Spain: RETROLUR, a real-world retrospective analysis using artificial intelligence by Fernando Mora, Carlos Gómez Sánchez-Lafuente, Mariano De Iceta, Carolina Roset, Antonio Cárdenas, Daniel Pérez, Elena Álvarez-Barón, Irene Gabarda-Inat, Savana Research Group (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11862477.txt.
Description
Mora and colleagues mined hospital records in twenty twenty-four to see how the antipsychotic drug lurasidone is really used in Spain. The drug treats schizophrenia and bipolar depression, but published data on everyday practice were scarce.
Using language-processing software, the team read the records of four hospitals and found two hundred seventy-two people who started the drug between twenty nineteen and twenty twenty-two. Most had tried a median of three earlier antipsychotics. Doses in practice stayed low, and under one percent of patients reached the highest doses. About seventeen percent stopped the drug during follow-up. Symptoms of psychosis, anxiety, and depression all grew less frequent after starting, and reported side effects fell compared with the period before. The authors say real-world use looks gentler than trial use. Low dosing, they note, may leave some benefit untapped.
Catalog record
| CREATOR | Fernando Mora, Carlos Gómez Sánchez-Lafuente, Mariano De Iceta, Carolina Roset, Antonio Cárdenas, Daniel Pérez, Elena Álvarez-Barón, Irene Gabarda-Inat, Savana Research Group |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |