A telomere-related signature for predicting prognosis and assessing immune microenvironment in osteosarcoma
Shihao Li, Lina Zhang, Haiyang Zhang · 2025
Read A telomere-related signature for predicting prognosis and assessing immune microenvironment in osteosarcoma by Shihao Li, Lina Zhang, Haiyang Zhang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11841432.txt.
Description
Shihao Li, Lina Zhang, and Haiyang Zhang present a 2024 study building a telomere-related gene signature for osteosarcoma prognosis. Bone cancer in the young invades and spreads aggressively. Telomere biology shapes cancer growth, so its genes might forecast outcomes.
Public tumour data sets fed survival models that selected ten telomere-related genes. The combined signature split patients by risk well. Immune settings and cell talk patterns differed between risk groups. Lab assays in cells checked growth, migration, and invasion. A telomere lens may help doctors judge which osteosarcomas need the hardest follow-up.
Catalog record
| CREATOR | Shihao Li, Lina Zhang, Haiyang Zhang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |