Metformin dosage and galectin-3 levels: insights from PCOS patients preparing for IVF

Valentina N. Nikolić, Milan Stefanović, Dejan Mitić, Slavica Sunarić, Vladana Stojiljkovic, Hristina Trajković, Aleksandra Ignjatović, Dragana Stokanović · 2025

Read Metformin dosage and galectin-3 levels: insights from PCOS patients preparing for IVF by Valentina N. Nikolić, Milan Stefanović, Dejan Mitić, Slavica Sunarić, Vladana Stojiljkovic, Hristina Trajković, Aleksandra Ignjatović, Dragana Stokanović (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11825798.txt.

Description

Valentina N. Nikolić and colleagues published a 2025 study of a diabetes drug in women with polycystic ovary syndrome. The women were preparing for fertility treatment. The drug metformin is commonly prescribed in this setting. A protein called galectin-3 may reflect metabolic state. The team varied by dose and hormone status.

Fifty-three women took part in the cohort. Drug levels and protein levels were measured precisely. Dose and high prolactin both tracked protein levels. Body weight showed no such link. Blood drug level alone predicted little. Duration and dose seemed to matter more. Findings support personalizing metformin dosing in fertility care.

Catalog record

CREATORValentina N. Nikolić, Milan Stefanović, Dejan Mitić, Slavica Sunarić, Vladana Stojiljkovic, Hristina Trajković, Aleksandra Ignjatović, Dragana Stokanović
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11825798

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