Comparison of double antibiotic chitosan hydrogel scaffold with platelet-rich fibrin in regeneration in immature necrotic permanent teeth – Randomized controlled trial
Neelam Mittal, Harakh Chand Baranwal, Harshitaa Aggarwal, Shubham Kharat, Silviya Samad, Aiyman Ayubi · 2024
Read Comparison of double antibiotic chitosan hydrogel scaffold with platelet-rich fibrin in regeneration in immature necrotic permanent teeth – Randomized controlled trial by Neelam Mittal, Harakh Chand Baranwal, Harshitaa Aggarwal, Shubham Kharat, Silviya Samad, Aiyman Ayubi (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11823575.txt.
Description
Neelam Mittal and co-authors compare scaffolds for regrowing dead young permanent teeth in a randomized trial. Their 2024 study enrolled fifty six teeth with open tips and lesions at the root end. Patients aged ten to thirty five were split into four groups. One group got platelet rich fibrin, a natural gel from blood. The others got chitosan gels: one plain, one with two antibiotics, and one matching gel without the chitosan.
Outcomes were read at twelve months with 3D scans, by blinded assessors. Root tip size, root length, wall thickness, and healing were measured. The antibiotic loaded chitosan gel gave the best regrowth results. It beat the fibrin and plain gel groups clearly. It did not differ significantly from the antibiotic gel without chitosan. One patient per group was lost to follow up. The authors favor antibiotic loaded gels for this regenerative task.
Catalog record
| CREATOR | Neelam Mittal, Harakh Chand Baranwal, Harshitaa Aggarwal, Shubham Kharat, Silviya Samad, Aiyman Ayubi |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |