Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection

Xinyi Shi, Shenghao Hua, Zeyuan Chen, Weiyi Cao, Mengqing Xiao, Wenlong Pei, Zhe Cao, Zhan Zhang, Haibing Yang, Xuejun Shao, Yu Xia · 2025

Read Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection by Xinyi Shi, Shenghao Hua, Zeyuan Chen, Weiyi Cao, Mengqing Xiao, Wenlong Pei, Zhe Cao, Zhan Zhang, Haibing Yang, Xuejun Shao, Yu Xia (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11821643.txt.

Description

Xinyi Shi and ten co-authors published a study in twenty twenty-five on what flu A does to a child's blood and airways at the level of small molecules and germs. They took blood and airway samples from eighty-five sick children and fifty-five controls with other chest illness. Two lab methods mapped blood chemistry and the airway germ mix.

The sick children showed broad shifts: fewer white cells and platelets, more red cells, and changed levels of fats and proteins in the blood. One chemical path, purine use, stood out as badly hit. It also split the two flu types, with one strain showing higher levels of three purine by-products. The airway germ mix shifted as well. The authors hope the map of changes will point to new ways to spot and treat flu in children early.

Catalog record

CREATORXinyi Shi, Shenghao Hua, Zeyuan Chen, Weiyi Cao, Mengqing Xiao, Wenlong Pei, Zhe Cao, Zhan Zhang, Haibing Yang, Xuejun Shao, Yu Xia
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11821643

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