Inhibitory Effects of Compounds Isolated from Morinda citrifolia L. (Noni) Seeds against Particulate Matter-Induced Injury
Thao Quyen Cao, Hyeongjin Eom, Hyukjin Kim, Ha Yeong Kang, Young Min Park, Sung Keun Jung, Dongyup Hahn · 2025
Read Inhibitory Effects of Compounds Isolated from Morinda citrifolia L. (Noni) Seeds against Particulate Matter-Induced Injury by Thao Quyen Cao, Hyeongjin Eom, Hyukjin Kim, Ha Yeong Kang, Young Min Park, Sung Keun Jung, Dongyup Hahn (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11813353.txt.
Description
Thao Quyen Cao and co-authors isolated compounds from noni seeds and tested them against air-pollution injury in airway cells, in a study published in 2024. Noni juice production throws the seeds away, yet they hold bioactive chemistry. The team extracted eight compounds, including four lignans, and confirmed their structures spectroscopically. They then challenged human bronchial cells with a pollutant chemical and measured survival.
All four lignans strongly protected the cells' viability, suggesting an anti-inflammatory role in airway disease. The result reframes a waste stream as a possible source of functional ingredients. The authors note the work is at the compound-and-cell stage. Animal and safety studies would be needed before any product claims. Still, the seed chemistry now has a first map and a promising lead.
Catalog record
| CREATOR | Thao Quyen Cao, Hyeongjin Eom, Hyukjin Kim, Ha Yeong Kang, Young Min Park, Sung Keun Jung, Dongyup Hahn |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |