Exploring the Proteomic Landscape and Immunomodulatory Functions of Edwardsiella piscicida Derived Extracellular Vesicles
Mawalle Kankanamge Hasitha Madhawa Dias, E.H.T. Thulshan Jayathilaka, Jayasinghage Nirmani Chathurangika Jayasinghe, Nipuna Tennakoon, Chamilani Nikapitiya, Ilson Whang, Mahanama De Zoysa · 2025
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Description
Mawalle Kankanamge Hasitha Madhawa Dias and co-authors study tiny sacs given off by a germ that makes fish sick, in a paper from 2025. The germ is called Edwardsiella piscicida. These sacs, known as extracellular vesicles, carry proteins and can change how the body fights infection.
The team used a fast spin method to collect the sacs and checked their size and shape. They found close to fifteen hundred distinct proteins inside, some linked to how the germ harms its host. The sacs did not poison fish cells in lab tests. In fish and cell tests, the sacs switched on genes tied to immune defense. The work points to a possible use in fish medicine.
Catalog record
| CREATOR | Mawalle Kankanamge Hasitha Madhawa Dias, E.H.T. Thulshan Jayathilaka, Jayasinghage Nirmani Chathurangika Jayasinghe, Nipuna Tennakoon, Chamilani Nikapitiya, Ilson Whang, Mahanama De Zoysa |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |