Aromadendrin Ameliorates Airway Inflammation in Experimental Mice with Chronic Obstructive Pulmonary Disease
Jinseon Choi, Seok Han Yun, Hyueyun Kim, Juhyun Lee, Seong-Man Kim, Mi-Hyeong Park, Hee Jae Lee, Wanjoo Chun, Sang-Bae Han, Kyung-Seop Ahn, Jae-Won Lee · 2025
Read Aromadendrin Ameliorates Airway Inflammation in Experimental Mice with Chronic Obstructive Pulmonary Disease by Jinseon Choi, Seok Han Yun, Hyueyun Kim, Juhyun Lee, Seong-Man Kim, Mi-Hyeong Park, Hee Jae Lee, Wanjoo Chun, Sang-Bae Han, Kyung-Seop Ahn, Jae-Won Lee (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11813338.txt.
Description
Jinseon Choi and co-authors present a study published in 2024 on a plant compound for chronic lung disease. The disease, COPD, narrows airways and brings long-term swelling. The compound, aromadendrin, is known to calm swelling, but its effect on this disease was unclear. The team tested it in mice bred to model the disease, giving it by mouth.
Treated mice had fewer immune cells and less toxic output in lung fluid. Lung tissue showed less cell influx and less mucus build-up. A protein tied to airway narrowing fell with treatment. The compound also blocked a chain of signals that drives swelling. The authors suggest it could serve as an add-on for care and prevention.
Catalog record
| CREATOR | Jinseon Choi, Seok Han Yun, Hyueyun Kim, Juhyun Lee, Seong-Man Kim, Mi-Hyeong Park, Hee Jae Lee, Wanjoo Chun, Sang-Bae Han, Kyung-Seop Ahn, Jae-Won Lee |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 15 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |