A Comparative Study of Bcl-2 Expression in Oral Leukoplakia with Dysplasia, Verrucous Carcinoma, and Oral Squamous Cell Carcinoma

Bireswar Roy, Shivani Saxena, Narayan Tripathi, Mridul Sharma, Deepmala Rana, N Pramukh, Miral Mehta · 2024

Read A Comparative Study of Bcl-2 Expression in Oral Leukoplakia with Dysplasia, Verrucous Carcinoma, and Oral Squamous Cell Carcinoma by Bireswar Roy, Shivani Saxena, Narayan Tripathi, Mridul Sharma, Deepmala Rana, N Pramukh, Miral Mehta (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11805061.txt.

Description

White patches in the mouth can stay harmless or turn toward cancer, and a protein that stops cell death may mark the turn. Bireswar Roy and co-authors compared that protein, Bcl-2, across mouth tissues in 2024. They stained eighty stored samples: precancerous patches at three grades, two kinds of mouth cancer, and normal lining as a control.

Staining grew stronger as the precancerous grades worsened and stronger still across the cancer grades. The pattern suggests Bcl-2 tracks the molecular march from patch to malignancy. The authors say such mapping could one day flag which patches need watching or removal, though their study stops at showing the gradient.

Catalog record

CREATORBireswar Roy, Shivani Saxena, Narayan Tripathi, Mridul Sharma, Deepmala Rana, N Pramukh, Miral Mehta
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE10 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11805061

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