Coupling of alternative splicing and alternative polyadenylation
Xueying Zhang, Feiyan Liu, Yu Zhou · 2024
Read Coupling of alternative splicing and alternative polyadenylation by Xueying Zhang, Feiyan Liu, Yu Zhou (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11802343.txt.
Description
Xueying Zhang, Feiyan Liu, and Yu Zhou review how two steps in RNA processing affect each other. Their 2024 review covers splicing, which cuts and rejoins RNA pieces, and polyadenylation, which adds a tail that ends the RNA. Both steps shape which proteins a cell can make.
The authors first outline the machines that run each step, then review studies of their cross-talk. Tail-making factors can help splice the last segment and can sway choices in inner segments too. Splicing, in turn, can compete with tail making inside segments and can change the length of the tail region. That length then feeds back on splicing choices. The review helps readers see RNA maturation as one linked system, not two separate lines.
Catalog record
| CREATOR | Xueying Zhang, Feiyan Liu, Yu Zhou |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |