Steering veridical large language model analyses by correcting and enriching generated database queries: first steps toward ChatGPT bioinformatics

Olivier Cinquin · 2025

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Description

Large language models (LLMs) leverage factual knowledge from pretraining. Yet this knowledge remains incomplete and sometimes challenging to retrieve—especially in scientific domains not extensively covered in pretraining datasets and where information is still evolving. Here, we focus on genomics and bioinformatics. We confirm and expand upon issues with plain ChatGPT functioning as a bioinformatics assistant.

Catalog record

CREATOROlivier Cinquin
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE39 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11798674

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