MicroRNA-219 in the central nervous system: a potential theranostic approach

Nahal Shamaeizadeh, Mina Mirian · 2024

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Description

Nahal Shamaeizadeh and Mina Mirian review a small brain RNA as a drug and diagnosis candidate in a paper from two thousand twenty-four. MicroRNAs tune gene activity by binding to messenger RNAs. One of them, microRNA-219, is rich in the brain and shapes nerve cell growth.

The molecule helps sheath-making cells mature and repair myelin, the insulation around nerve fibers. That makes it a candidate for multiple sclerosis and spinal cord injury. It also steers the body clock, touches mood stability, and curbs tau harm seen in Alzheimer's disease. Reports add protection against seizures and Parkinson's disease, plus anti-tumor effects. The authors map its pathways for future gene therapy.

Catalog record

CREATORNahal Shamaeizadeh, Mina Mirian
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE60 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11792714

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