Ingested house dust mite favors sensitization to egg white in mice independently of its proteinase activity
Sara Benedé, Leticia Pérez-Rodríguez, David Menchén-Martínez, Elena Molina, Rosina López-Fandiño · 2025
Read Ingested house dust mite favors sensitization to egg white in mice independently of its proteinase activity by Sara Benedé, Leticia Pérez-Rodríguez, David Menchén-Martínez, Elena Molina, Rosina López-Fandiño (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11788175.txt.
Description
Sara Benedé and four co-authors show, in work published in 2024, that dust mites eaten by mice can prime them for egg allergy. Mites in house dust are known to harm airways, but their role in food allergy through the gut was little probed. The team fed mice mite extract with egg white, with no extra booster.
Both live mite extract and a form with its cutting enzymes killed primed the mice, as shown by gut mast cell bursts when egg was fed later. The killed form even raised egg-specific blood marks that the live form did not. Gut wall and alarm genes rose more under the live form, yet the killed form drove the allergy-type reply in gut lymph tissue. The team warns that swallowed dust may feed food allergy.
Catalog record
| CREATOR | Sara Benedé, Leticia Pérez-Rodríguez, David Menchén-Martínez, Elena Molina, Rosina López-Fandiño |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |