Inflammatory biomarkers and therapeutic potential of milk exosome-mediated CCL7 siRNA in murine intestinal ischemia-reperfusion injury
WenDong Chen, WenPing Xu, Li Ma, Chun Bi, MeiXu Yang, Wei Yang · 2025
Read Inflammatory biomarkers and therapeutic potential of milk exosome-mediated CCL7 siRNA in murine intestinal ischemia-reperfusion injury by WenDong Chen, WenPing Xu, Li Ma, Chun Bi, MeiXu Yang, Wei Yang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11788141.txt.
Description
WenDong Chen and co-authors hunt for warning markers and a treatment for gut injury that strikes when blood flow returns after a blockage. The condition carries high illness and death rates, and good tests and treatments are scarce. Their study, dated 2024 in the head, starts from gene reading in a mouse model of the injury.
One gene stood out as a hub, switched on far more in injured guts. The team loaded milk-derived tiny bubbles with a silencer for that gene and gave them to the mice. Treated mice showed less gut damage under the microscope, better gut wall markers in blood, and calmer body-wide swelling. The authors present the bubble delivery route as a promising new way to treat this injury.
Catalog record
| CREATOR | WenDong Chen, WenPing Xu, Li Ma, Chun Bi, MeiXu Yang, Wei Yang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |