Enhancement of host defense against Helicobacter pylori infection through modulation of the gastrointestinal microenvironment by Lactiplantibacillus plantarum Lp05

Yao Dong, Mei Han, Yongmei Qi, Ying Wu, Zhipeng Zhou, Dacheng Jiang, Zhonghui Gai · 2025

Read Enhancement of host defense against Helicobacter pylori infection through modulation of the gastrointestinal microenvironment by Lactiplantibacillus plantarum Lp05 by Yao Dong, Mei Han, Yongmei Qi, Ying Wu, Zhipeng Zhou, Dacheng Jiang, Zhonghui Gai (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11782045.txt.

Description

A friendly gut bacterium may help evict the stomach's most notorious tenant, and Yao Dong and co-authors test one strain in mice infected with Helicobacter pylori. The record shows the work published in 2024, a year earlier than the catalog lists. In dishes the probiotic clumped with the pathogen and damaged its cells; in mice it cut stomach colonization.

Treated mice showed lower infection markers, calmer stomach tissue, and stronger antioxidant defenses, while their gut and stomach communities shifted toward friendlier species. The dose mattered across the three levels tried. The authors back the strain as a probiotic candidate needing refinement.

Catalog record

CREATORYao Dong, Mei Han, Yongmei Qi, Ying Wu, Zhipeng Zhou, Dacheng Jiang, Zhonghui Gai
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE47 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11782045

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