Destined for destruction: The role of methionine aminopeptidases and plant cysteine oxidases in N-degron formation
Andrea Fuentes-Terrón, Rebecca Latter, Samuel Madden, Isabel Manrique-Gil, Jessenia Estrada, Noelia Arteaga, Inmaculada Sánchez-Vicente, Oscar Lorenzo, Emily Flashman · 2025
Read Destined for destruction: The role of methionine aminopeptidases and plant cysteine oxidases in N-degron formation by Andrea Fuentes-Terrón, Rebecca Latter, Samuel Madden, Isabel Manrique-Gil, Jessenia Estrada, Noelia Arteaga, Inmaculada Sánchez-Vicente, Oscar Lorenzo, Emily Flashman (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11773813.txt.
Description
Andrea Fuentes-Terrón and co-authors review enzymes that set up proteins for destruction through the N-degron pathway in plants. Their paper, reported in 2024, deals with the cysteine and arginine branch of that pathway.
This branch controls proteins that start with methionine followed by cysteine, once the methionine is cut and the cysteine is oxidized. Targets include factors that drive responses to low oxygen, and proteins tied to developmental hypoxia. Two enzyme groups control their start: methionine aminopeptidases and plant cysteine oxidases. The review covers what these enzymes bind and how well they act, since those traits decide which proteins are degraded and when.
Catalog record
| CREATOR | Andrea Fuentes-Terrón, Rebecca Latter, Samuel Madden, Isabel Manrique-Gil, Jessenia Estrada, Noelia Arteaga, Inmaculada Sánchez-Vicente, Oscar Lorenzo, Emily Flashman |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |