Case report: Overlapping syndrome of MOG-IgG associated optic neuritis and autoimmune encephalitis with co-existence of anti-NMDAR and anti-GABABR antibodies

Zhujun Mei, Jingguo Wang, Junling Wang, Xiaoni Liu, Bo Deng, Wenbo Yang, Xiang Zhang, Xiangjun Chen, Hai Yu · 2025

Read Case report: Overlapping syndrome of MOG-IgG associated optic neuritis and autoimmune encephalitis with co-existence of anti-NMDAR and anti-GABABR antibodies by Zhujun Mei, Jingguo Wang, Junling Wang, Xiaoni Liu, Bo Deng, Wenbo Yang, Xiang Zhang, Xiangjun Chen, Hai Yu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11772160.txt.

Description

Zhujun Mei, Jingguo Wang, and others report a single patient whose illness joined several autoimmune attacks on the nervous system at once in a 2025 case report. The patient's optic neuritis, inflammation of the optic nerve, came with autoimmune encephalitis. Blood tests found three relevant antibodies together: against a glutamate receptor, a GABA receptor, and the myelin protein targeted in a related disease family.

Overlapping antibody syndromes are rare and hard to spot, since each antibody alone suggests a different treatment path. Writing up the combination helps clinicians test broadly when a case refuses to fit one diagnosis.

Catalog record

CREATORZhujun Mei, Jingguo Wang, Junling Wang, Xiaoni Liu, Bo Deng, Wenbo Yang, Xiang Zhang, Xiangjun Chen, Hai Yu
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE17 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11772160

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