Osmotic Demyelination Syndrome in the Setting of Normonatremia: A Case Report and Review of the Literature

Rose V. Zach, Jeffrey F. Barletta, Victor Zach · 2024

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Description

A rare brain injury called osmotic demyelination syndrome usually follows sodium levels corrected too fast in people whose sodium was very low. Rose Zach, Jeffrey Barletta, and Victor Zach describe a case where the starting sodium was normal. Their patient, a 57-year-old woman treated after a fall, saw her sodium climb sharply over two days.

She developed one-sided weakness that spared her face, and brain scans showed the classic injury spot at the center of the pons. Doctors lowered her sodium slowly, and four years later she still needed some help with daily life. The authors also review twenty-three published cases like hers. Alcohol problems, dialysis, and kidney disease appear often in those reports. They urge doctors to suspect this injury even when sodium starts normal.

Catalog record

CREATORRose V. Zach, Jeffrey F. Barletta, Victor Zach
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE17 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11772055

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