ZW10: an emerging orchestrator of organelle dynamics during the cell division cycle

Sm Faysal Bellah, Fengrui Yang, Fangyuan Xiong, Zhen Dou, Xuebiao Yao, Xing Liu, Jiarui Wu · 2024

Read ZW10: an emerging orchestrator of organelle dynamics during the cell division cycle by Sm Faysal Bellah, Fengrui Yang, Fangyuan Xiong, Zhen Dou, Xuebiao Yao, Xing Liu, Jiarui Wu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11757092.txt.

Description

Faysal Bellah and colleagues review ZW10 as a cell cycle traffic chief, in work from 2024. ZW10 was first found at the chromosome grip point in fruit flies years ago. It guides the safety check that guards equal chromosome splits in animal cells.

New work adds a second life for ZW10 between division rounds in the cell. It links membrane sacs and steers cargo flow between cell factory zones. Its partner sets shift with cycle phase, forming context bound complexes each time. Those complexes run membrane traffic in rest phase and grip checks in division. Open questions remain on how one protein steers both jobs with such precision.

Catalog record

CREATORSm Faysal Bellah, Fengrui Yang, Fangyuan Xiong, Zhen Dou, Xuebiao Yao, Xing Liu, Jiarui Wu
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11757092

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