Enhanced infectivity of bovine viral diarrhoea virus (BVDV) in arginase-producing bovine monocyte-derived macrophages
Lucas José Barone, Nancy Patricia Cardoso, Florencia Celeste Mansilla, Mariángeles Castillo, Alejandra Victoria Capozzo · 2023
Read Enhanced infectivity of bovine viral diarrhoea virus (BVDV) in arginase-producing bovine monocyte-derived macrophages by Lucas José Barone, Nancy Patricia Cardoso, Florencia Celeste Mansilla, Mariángeles Castillo, Alejandra Victoria Capozzo (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11756584.txt.
Description
Barone and four colleagues study a cattle virus in work published in twenty twenty-four. The virus causes bovine viral diarrhoea and can weaken the immune system. The team looks at macrophages, which are immune cells grown from blood cells. These cells can take a pro-inflammatory form or a calmer form linked to an enzyme called arginase.
Cells with high arginase let the virus copy itself faster, for varied virus types. Blocking arginase cut how well the virus could infect the cells. A drug given to calves pushed their cells toward the calmer form and raised arginase. Cells from pregnant cows and calves also made more arginase than cells from other adults. The findings suggest the calmer cells may help the virus persist.
Catalog record
| CREATOR | Lucas José Barone, Nancy Patricia Cardoso, Florencia Celeste Mansilla, Mariángeles Castillo, Alejandra Victoria Capozzo |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |