Suspected heparin-induced thrombocytopaenia in pulmonary thromboendarterectomy: retrospective cohort

Guillaume Guimbretière, Clément Dubost, Justin Issard, Virginie Louvain-Quintard, Xavier Jais, Samuel Dolidon, François Stephan, Daniela-Iolanda Ion, Olaf Mercier, Elie Fadel · 2025

Read Suspected heparin-induced thrombocytopaenia in pulmonary thromboendarterectomy: retrospective cohort by Guillaume Guimbretière, Clément Dubost, Justin Issard, Virginie Louvain-Quintard, Xavier Jais, Samuel Dolidon, François Stephan, Daniela-Iolanda Ion, Olaf Mercier, Elie Fadel (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11754861.txt.

Description

Guimbretière and nine co-authors review suspected cases of a dangerous heparin reaction after lung artery surgery for chronic clots. The reaction, where the blood thinner drops platelet counts and can cause clots, was suspected in 86 of 1,360 patients. Only 16 cases were confirmed by both antibody and platelet tests.

Every confirmed patient got replacement therapy and survived the intensive care stay. Among unconfirmed cases, those given replacement therapy bled less and died less often than those who were not. A sharp platelet fall on day five marked the confirmed cases. The authors offer the patterns as guidance for a murky diagnosis. The study appeared in 2024.

Catalog record

CREATORGuillaume Guimbretière, Clément Dubost, Justin Issard, Virginie Louvain-Quintard, Xavier Jais, Samuel Dolidon, François Stephan, Daniela-Iolanda Ion, Olaf Mercier, Elie Fadel
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11754861

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