Outcomes of Direct-Acting Antivirals Versus Interferon-Based Therapy in Chronic Hepatitis C Infection
Ratna Chowdhury, Wardah Rashid, Taranpreet Singh, Abdur Rehman, Nida F Daterdiwala, Varaidzo Mkosi, Bhumikala Limbu, Syeda Alliza Bukhari, Afif Ramadhan, Muath M Dabas, Abdullah Shehryar, Ramadan Khan · 2024
Read Outcomes of Direct-Acting Antivirals Versus Interferon-Based Therapy in Chronic Hepatitis C Infection by Ratna Chowdhury, Wardah Rashid, Taranpreet Singh, Abdur Rehman, Nida F Daterdiwala, Varaidzo Mkosi, Bhumikala Limbu, Syeda Alliza Bukhari, Afif Ramadhan, Muath M Dabas, Abdullah Shehryar, Ramadan Khan (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11738830.txt.
Description
Hepatitis C treatment changed when direct-acting antivirals replaced the older interferon-based regimens, and Ratna Chowdhury and co-authors review how the two eras compare. Their systematic review gathers studies of patients with chronic hepatitis C, including hard cases such as people with cirrhosis and those who had failed earlier treatment.
Across the studies, the newer drugs cleared the virus at higher rates, measured as sustained response after treatment. They also caused fewer side effects, with less anemia and fatigue, which made long courses easier to finish. The authors name the antivirals the standard of care, including for special groups once considered hard to treat. Interferon still matters where money is tight, they note, but widening access to the newer drugs is the surest route to cutting hepatitis C deaths.
Catalog record
| CREATOR | Ratna Chowdhury, Wardah Rashid, Taranpreet Singh, Abdur Rehman, Nida F Daterdiwala, Varaidzo Mkosi, Bhumikala Limbu, Syeda Alliza Bukhari, Afif Ramadhan, Muath M Dabas, Abdullah Shehryar, Ramadan Khan |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |