Undernutrition-induced stunting-like phenotype in Drosophila melanogaster
Tenri ZAD Putri, Elly Wahyudin, Muhammad R Pratama, Dewita Fatiah, Widya Hardiyanti, Rizkya Chaeratunnisa, Nadila P Latada, Fatmawati Fatmawati, Mukarram Mudjahid, Firzan Nainu · 2024
Read Undernutrition-induced stunting-like phenotype in Drosophila melanogaster by Tenri ZAD Putri, Elly Wahyudin, Muhammad R Pratama, Dewita Fatiah, Widya Hardiyanti, Rizkya Chaeratunnisa, Nadila P Latada, Fatmawati Fatmawati, Mukarram Mudjahid, Firzan Nainu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11731816.txt.
Description
Tenri Putri and nine co-authors build a fruit-fly model of childhood stunting, in a 2024 study. Stunting from poor food blights growth worldwide, yet its inner workings are faint. Flies share many growth signals with back-boned animals, which makes them a cheap stand-in. The team fed larvae full food or food cut to half, quarter, and eighth strength across sugar, yeast, and meal parts.
Starved flies grew stunted: smaller bodies, fewer offspring, and worse odds of survival, though their movement stayed normal. Gene reads inside the flies shifted in telling ways. A stress gene fell, while genes for metabolism, cell growth, and survival moved in patterns the team maps. The fly model gives labs a fast way to probe how hunger writes itself into the body, and to test fixes before mammal work.
Catalog record
| CREATOR | Tenri ZAD Putri, Elly Wahyudin, Muhammad R Pratama, Dewita Fatiah, Widya Hardiyanti, Rizkya Chaeratunnisa, Nadila P Latada, Fatmawati Fatmawati, Mukarram Mudjahid, Firzan Nainu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |