Multigenerational Consequences of Prenatal Exposure to Benzophenone-3 Demonstrate Sex- and Region-Dependent Neurotoxic and Pro-Apoptotic Effects in Mouse Brain
Karolina Przepiórska-Drońska, Andrzej Łach, Bernadeta Angelika Pietrzak-Wawrzyńska, Joanna Rzemieniec, Małgorzata Kajta, Agnieszka Wawrzczak-Bargieła, Wiktor Bilecki, Karolina Noworyta, Agnieszka Wnuk, Wei Xia · 2024
Read Multigenerational Consequences of Prenatal Exposure to Benzophenone-3 Demonstrate Sex- and Region-Dependent Neurotoxic and Pro-Apoptotic Effects in Mouse Brain by Karolina Przepiórska-Drońska, Andrzej Łach, Bernadeta Angelika Pietrzak-Wawrzyńska, Joanna Rzemieniec, Małgorzata Kajta, Agnieszka Wawrzczak-Bargieła, Wiktor Bilecki, Karolina Noworyta, Agnieszka Wnuk, Wei Xia (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11728767.txt.
Description
Karolina Przepiórska-Drońska and co-authors test whether a common sunscreen filter harms the developing brain across generations, published in 2024. The chemical, benzophenone-3, is used in personal care products and as a stabilizer. It is suspected of disrupting hormones, yet its effects on brain growth over more than one generation were little studied.
The team exposed mother mice to levels like those found in the environment. They then checked markers of cell damage and cell death in two brain regions, in both the first and second generations. Effects differed by sex and by region. Signs of death through an external cell pathway rose most, and effects were stronger in the first generation than the second.
Catalog record
| CREATOR | Karolina Przepiórska-Drońska, Andrzej Łach, Bernadeta Angelika Pietrzak-Wawrzyńska, Joanna Rzemieniec, Małgorzata Kajta, Agnieszka Wawrzczak-Bargieła, Wiktor Bilecki, Karolina Noworyta, Agnieszka Wnuk, Wei Xia |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |