Detection of Total Aflatoxins in Herbal Medicines Based on Lateral Flow Assay with Contamination Ratio Model
Xiao-Ya Qin, Rui Feng, Heng Zhou, Hui-Qin Pan, Hao Wang, Xiao-Jing Huang, Jian-Ying Shen, Qing Hu, Shen Ji, Victoria Samanidou · 2024
Read Detection of Total Aflatoxins in Herbal Medicines Based on Lateral Flow Assay with Contamination Ratio Model by Xiao-Ya Qin, Rui Feng, Heng Zhou, Hui-Qin Pan, Hao Wang, Xiao-Jing Huang, Jian-Ying Shen, Qing Hu, Shen Ji, Victoria Samanidou (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11728669.txt.
Description
Xiao-Ya Qin and co-authors built a paper-strip test for measuring poisons from mold in herbal medicines, in this 2024 study. Aflatoxins, made by fungi that colonize stored plants, are potent liver toxins, and herbal products are rarely screened fast enough. Standard lab methods are accurate but slow and costly.
Their strip uses gold-labeled antibodies that change color in proportion to toxin levels, read by a small digital device. The trick is calibration: each herb's plant matrix distorts the signal differently, so they fitted contamination-ratio models matched to five seed medicines. The test measured totals from 2.5 to 40 micrograms per kilogram, detecting as little as one. Across 229 samples, results tracked the reference lab method reasonably well. A pocket test with honest numbers could let inspectors screen herbal supplies at the warehouse door.
Catalog record
| CREATOR | Xiao-Ya Qin, Rui Feng, Heng Zhou, Hui-Qin Pan, Hao Wang, Xiao-Jing Huang, Jian-Ying Shen, Qing Hu, Shen Ji, Victoria Samanidou |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |