Detrimental Effects of Anti-Nucleocapsid Antibodies in SARS-CoV-2 Infection, Reinfection, and the Post-Acute Sequelae of COVID-19

Emi E Nakayama, Tatsuo Shioda, Yuntao Wu · 2024

Read Detrimental Effects of Anti-Nucleocapsid Antibodies in SARS-CoV-2 Infection, Reinfection, and the Post-Acute Sequelae of COVID-19 by Emi E Nakayama, Tatsuo Shioda, Yuntao Wu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11728538.txt.

Description

Emi Nakayama and Tatsuo Shioda review a way antibodies can worsen COVID-19 rather than guard against it. Their 2024 review centers on antibodies aimed at the virus core protein, as distinct from those aimed at its spike. In some settings the core antibodies spur immune cells to pour out signal proteins.

That flood may drive severe illness when a person meets the virus a second time, the authors argue. It may also feed the long tail of symptoms that can last three months or more after the first illness. The review sets this path beside two spike-based paths of the same broad kind. New spike antibodies that block recent variants get a brief note as a counterpoint.

Catalog record

CREATOREmi E Nakayama, Tatsuo Shioda, Yuntao Wu
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE31 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11728538

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