Comparative Analysis of the Effects of Maternal Hypoxia and Placental Ischemia on HIF1-Dependent Metabolism and the Glucocorticoid System in the Embryonic and Newborn Rat Brain
Oleg Vetrovoy, Sofiya Potapova, Viktor Stratilov, Ekaterina Tyulkova · 2024
Read Comparative Analysis of the Effects of Maternal Hypoxia and Placental Ischemia on HIF1-Dependent Metabolism and the Glucocorticoid System in the Embryonic and Newborn Rat Brain by Oleg Vetrovoy, Sofiya Potapova, Viktor Stratilov, Ekaterina Tyulkova (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11727977.txt.
Description
Oleg Vetrovoy, Sofiya Potapova, Viktor Stratilov, and Ekaterina Tyulkova present a 2024 study of how low oxygen before birth affects the growing rat brain. Low oxygen in the womb can raise the risk of brain problems later in life. Two causes can look alike but act in distinct ways.
One model cuts blood flow through the placenta, which mainly cuts the oxygen supply. The other lowers oxygen for the mother, which also floods the fetus with stress hormones. The team compared both models in unborn and newborn rats. They tracked hormone flow into the brain, the sensors that read those hormones, and genes that switch on when oxygen runs low.
Catalog record
| CREATOR | Oleg Vetrovoy, Sofiya Potapova, Viktor Stratilov, Ekaterina Tyulkova |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |