Novel Selectable Marker Sesquiterpenoid Antibiotic Pentalenolactone
Arina A Nikandrova, Anna D Petriakova, Anton R Izzi, Garegin A Petrosyan, Vadim N Tashlitsky, Vera A Alferova, Tatiana V Panova, Maria G Khrenova, Mikhail V Biryukov, Yuliya V Zakalyukina, Maria I Zvereva, Dmitrii A Lukianov, Petr V Sergiev, Mariusz Cycoń · 2024
Read Novel Selectable Marker Sesquiterpenoid Antibiotic Pentalenolactone by Arina A Nikandrova, Anna D Petriakova, Anton R Izzi, Garegin A Petrosyan, Vadim N Tashlitsky, Vera A Alferova, Tatiana V Panova, Maria G Khrenova, Mikhail V Biryukov, Yuliya V Zakalyukina, Maria I Zvereva, Dmitrii A Lukianov, Petr V Sergiev, Mariusz Cycoń (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11727764.txt.
Description
Nikandrova and co-authors study a little-known antibiotic made by soil bacteria, and propose it as a new marker for gene work. Antibiotic resistance is a growing threat, and one answer is to study how natural antibiotics act. Bacteria from poorly studied habitats, where food is scarce and rivalry is fierce, are promising sources of such compounds.
The team isolated a bacterial strain from desert soil and identified the antibiotic it makes, a ring-shaped molecule called pentalenolactone. They explore how it kills or stops other bacteria and how its own producer resists it. A compound with a fresh mode of action can serve as a selectable marker in the lab. The work adds a tool for genetic studies of bacteria.
Catalog record
| CREATOR | Arina A Nikandrova, Anna D Petriakova, Anton R Izzi, Garegin A Petrosyan, Vadim N Tashlitsky, Vera A Alferova, Tatiana V Panova, Maria G Khrenova, Mikhail V Biryukov, Yuliya V Zakalyukina, Maria I Zvereva, Dmitrii A Lukianov, Petr V Sergiev, Mariusz Cycoń |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |