Tumor Necrosis Factor Superfamily 14 Regulates the Inflammatory Response of Human Dental Pulp Stem Cells
Abdulelah Alrshedan, Mona Elsafadi, Manikandan Muthurangan, Solaiman Al-Hadlaq · 2024
Read Tumor Necrosis Factor Superfamily 14 Regulates the Inflammatory Response of Human Dental Pulp Stem Cells by Abdulelah Alrshedan, Mona Elsafadi, Manikandan Muthurangan, Solaiman Al-Hadlaq (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11727631.txt.
Description
Abdulelah Alrshedan and co-authors test an immune signal on inflamed tooth pulp cells in a 2024 study. Tooth decay is widespread and often ends in pulp inflammation. Ideal care calms the pulp rather than killing it. A TNF family signal, TNFSF14, may tune that inflammation.
Human dental pulp stem cells were inflamed with a bacterial wall piece. The signal was then added at two doses. Treated cells lived better than untreated inflamed ones. Bad actor cytokines fell in both message and protein terms. A calming cytokine rose in step. The results nominate the signal as a pulp-soothing candidate for future dental materials.
Catalog record
| CREATOR | Abdulelah Alrshedan, Mona Elsafadi, Manikandan Muthurangan, Solaiman Al-Hadlaq |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |