Integrating Gene Expression Data into Single-Step Method (ssBLUP) Improves Genomic Prediction Accuracy for Complex Traits of Duroc × Erhualian F2 Pig Population
Fangjun Xu, Zhaoxuan Che, Jiakun Qiao, Pingping Han, Na Miao, Xiangyu Dai, Yuhua Fu, Xinyun Li, Mengjin Zhu · 2024
Read Integrating Gene Expression Data into Single-Step Method (ssBLUP) Improves Genomic Prediction Accuracy for Complex Traits of Duroc × Erhualian F2 Pig Population by Fangjun Xu, Zhaoxuan Che, Jiakun Qiao, Pingping Han, Na Miao, Xiangyu Dai, Yuhua Fu, Xinyun Li, Mengjin Zhu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11727526.txt.
Description
Fangjun Xu and co-authors fold gene expression data into genomic prediction for pig traits. Breeders forecast complex traits from DNA, yet expression data speak more directly of gene action. Their single-step method blends pedigree, genotypes, and expression in one model. A Duroc by Erhualian cross population supplied fifty-four traits to test.
Accuracy rose for over ninety percent of traits with expression added. Average gains topped twenty percent over pedigree-only prediction at one setting. Genome-only prediction trailed by about twelve percent in the same runs. The classic single-step method also fell behind by about five percent. Multi-layer data thus pays off in practice.
Catalog record
| CREATOR | Fangjun Xu, Zhaoxuan Che, Jiakun Qiao, Pingping Han, Na Miao, Xiangyu Dai, Yuhua Fu, Xinyun Li, Mengjin Zhu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |