Interplay of Oxidative Stress, Gut Microbiota, and Nicotine in Metabolic-Associated Steatotic Liver Disease (MASLD)
Irene Mignini, Linda Galasso, Giulia Piccirilli, Valentin Calvez, Fabrizio Termite, Giorgio Esposto, Raffaele Borriello, Luca Miele, Maria Elena Ainora, Antonio Gasbarrini, Maria Assunta Zocco, Sunmin Park · 2024
Read Interplay of Oxidative Stress, Gut Microbiota, and Nicotine in Metabolic-Associated Steatotic Liver Disease (MASLD) by Irene Mignini, Linda Galasso, Giulia Piccirilli, Valentin Calvez, Fabrizio Termite, Giorgio Esposto, Raffaele Borriello, Luca Miele, Maria Elena Ainora, Antonio Gasbarrini, Maria Assunta Zocco, Sunmin Park (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11727446.txt.
Description
Irene Mignini and co-authors review how smoking, gut microbes, and cell damage feed a common fatty liver disease, in a paper published in 2024. In this disease, extra fat builds up in the liver alongside wider metabolic trouble. Harmful oxygen by-products are known to be one of its main drivers.
Nicotine, the authors argue, makes matters worse: it raises swelling and cell damage, frees fat from belly stores, and pushes the liver to make more fat. At the same time, nicotine-driven damage reshapes the gut microbe mix, and a disturbed gut in turn helps drive the liver disease. The review maps this three-way web at the level of molecules. Its aim is to show where the chain might be broken by treatment.
Catalog record
| CREATOR | Irene Mignini, Linda Galasso, Giulia Piccirilli, Valentin Calvez, Fabrizio Termite, Giorgio Esposto, Raffaele Borriello, Luca Miele, Maria Elena Ainora, Antonio Gasbarrini, Maria Assunta Zocco, Sunmin Park |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |