Oxidative Stress Induced by Antivirals: Implications for Adverse Outcomes During Pregnancy and in Newborns
Bárbara Costa, Maria João Gouveia, Nuno Vale, Jadwiga Ambroszkiewicz, Magdalena Chełchowska, Joanna Gajewska · 2024
Read Oxidative Stress Induced by Antivirals: Implications for Adverse Outcomes During Pregnancy and in Newborns by Bárbara Costa, Maria João Gouveia, Nuno Vale, Jadwiga Ambroszkiewicz, Magdalena Chełchowska, Joanna Gajewska (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11727424.txt.
Description
Bárbara Costa and co-authors review a dilemma in treating infections during pregnancy: the drugs that protect mother and fetus may harm their cells. Their 2024 review examines how antiviral medicines, especially those used against HIV and the coronavirus, can raise oxidative stress. Pregnancy already shifts the body's balance, and drug handling changes with it.
Some studies link these drugs to cell stress and mitochondrial strain in pregnancy; others find their use generally safe. The authors map that conflict honestly, including what remains unknown. They survey natural defenses and ways to blunt the damage without weakening antiviral power. The stakes are uneven: untreated infection is certainly dangerous, while drug harms are suspected and long-term. Their call is for research that can weigh both sides, including follow-up of exposed children, rather than reassurance by default.
Catalog record
| CREATOR | Bárbara Costa, Maria João Gouveia, Nuno Vale, Jadwiga Ambroszkiewicz, Magdalena Chełchowska, Joanna Gajewska |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 77 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |