Oligomeric Proanthocyanidins Ameliorate Cadmium-Induced Senescence of Osteocytes Through Combating Oxidative Stress and Inflammation
Gengsheng Yu, Zehao Wang, Anqing Gong, Xiaohui Fu, Naineng Chen, Dehui Zhou, Yawen Li, Zongping Liu, Xishuai Tong · 2024
Read Oligomeric Proanthocyanidins Ameliorate Cadmium-Induced Senescence of Osteocytes Through Combating Oxidative Stress and Inflammation by Gengsheng Yu, Zehao Wang, Anqing Gong, Xiaohui Fu, Naineng Chen, Dehui Zhou, Yawen Li, Zongping Liu, Xishuai Tong (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11727362.txt.
Description
Gengsheng Yu and co-authors tested grape seed compounds against cadmium-driven bone cell aging in a 2024 paper. Cadmium is a wide-spread pollutant that damages bone. It pushes osteocytes, the bone maintenance cells, into early senescence. Oligomeric proanthocyanidins from plants show anti-aging promise.
In lab cultures, the compounds eased the cadmium effect. Cell cycle arrest eased and reactive oxygen fell. Inflammatory signals quieted as well. The dendrite-like links between bone cells stayed intact. The results name a possible shield for polluted settings. Animal proof and dose studies would be the natural next step.
Catalog record
| CREATOR | Gengsheng Yu, Zehao Wang, Anqing Gong, Xiaohui Fu, Naineng Chen, Dehui Zhou, Yawen Li, Zongping Liu, Xishuai Tong |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |