Automated Supraclavicular Brown Adipose Tissue Segmentation in Computed Tomography Using nnU-Net: Integration with TotalSegmentator

Kasper Jørgensen, Frederikke Engel Høi-Hansen, Ruth J F Loos, Christian Hinge, Flemming Littrup Andersen, Zhuhuang Zhou · 2024

Read Automated Supraclavicular Brown Adipose Tissue Segmentation in Computed Tomography Using nnU-Net: Integration with TotalSegmentator by Kasper Jørgensen, Frederikke Engel Høi-Hansen, Ruth J F Loos, Christian Hinge, Flemming Littrup Andersen, Zhuhuang Zhou (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11727111.txt.

Description

Kasper Jørgensen and co-authors teach a neural network to outline brown fat in CT scans, in a 2024 study. Brown fat burns energy to make heat, so it draws interest in metabolism research. Tracing it by hand in scans is slow and varies between readers.

The team trained a 3D nnU-Net on hand-drawn outlines from 159 lymphoma patients and merged it into a public body-mapping tool. On 30 fresh patients the model scored a DICE overlap of 0.780, a solid match with human tracings. The team also mined over 7,000 PET/CT studies for brown fat activity patterns, finding gaps between the sexes. Fast auto-tracing opens large scan archives to brown fat research.

Catalog record

CREATORKasper Jørgensen, Frederikke Engel Høi-Hansen, Ruth J F Loos, Christian Hinge, Flemming Littrup Andersen, Zhuhuang Zhou
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11727111

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