Beta-Thalassemia and Male Infertility: Unraveling the Oxidative Stress Connection—An Up-to-Date Review
Christos Roidos, Christos-Alexandros Batakoias, Evangelos N Symeonidis, Aris Kaltsas, Vasileios Tzikoulis, Georgios Tsampoukas, Chara Tsiampali, Natalia Palapela, Athanasios Zachariou, Nikolaos Sofikitis, Fotios Dimitriadis, Theo M de Reijke · 2024
Read Beta-Thalassemia and Male Infertility: Unraveling the Oxidative Stress Connection—An Up-to-Date Review by Christos Roidos, Christos-Alexandros Batakoias, Evangelos N Symeonidis, Aris Kaltsas, Vasileios Tzikoulis, Georgios Tsampoukas, Chara Tsiampali, Natalia Palapela, Athanasios Zachariou, Nikolaos Sofikitis, Fotios Dimitriadis, Theo M de Reijke (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11727083.txt.
Description
Christos Roidos and co-authors review in this 2024 paper how oxidative stress links an inherited blood disorder to male infertility. Beta-thalassemia forces regular transfusions, and the iron they bring overloads the body. Seventy-one studies passed the team's screen on fertility, hormones, and stress damage in these men.
The iron rusts sperm from inside: quality falls, sex hormones sag, and the glands that drive them falter. Antioxidant therapies show promise at limiting the damage, though solid trials are scarce. The authors call for tailored antioxidant plans and deeper work on the stress pathways, so treatment can be matched to each patient's load. Clinics could screen sperm health far earlier.
Catalog record
| CREATOR | Christos Roidos, Christos-Alexandros Batakoias, Evangelos N Symeonidis, Aris Kaltsas, Vasileios Tzikoulis, Georgios Tsampoukas, Chara Tsiampali, Natalia Palapela, Athanasios Zachariou, Nikolaos Sofikitis, Fotios Dimitriadis, Theo M de Reijke |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |