Effect of Alkanna tinctoria Root Against MRSA and MDR-Pseudomonas aeruginosa Biofilms on Excision Wound in Diabetic Mice: Comparative Study Between Methanolic Extract and Traditional Hydrophobic Preparation
Yasir Almuhanna, Mohammed Asad, Mohammed S. Alshammari, Babu Joseph · 2024
Read Effect of Alkanna tinctoria Root Against MRSA and MDR-Pseudomonas aeruginosa Biofilms on Excision Wound in Diabetic Mice: Comparative Study Between Methanolic Extract and Traditional Hydrophobic Preparation by Yasir Almuhanna, Mohammed Asad, Mohammed S. Alshammari, Babu Joseph (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11726994.txt.
Description
Yasir Almuhanna and co-authors tested a traditional root remedy against drug-resistant wound infections in diabetic mice in a 2024 study. Alkanna tinctoria, called dyer's alkanet, is used in Saudi folk medicine for skin infections. The test germs were tough ones: MRSA and a multidrug-resistant Pseudomonas, both forming biofilms that shield them from drugs.
The team compared a methanol extract of the root with the traditional oil-based folk preparation on cut wounds. Chemical analysis profiled the extract's contents. Diabetic wounds heal slowly and infect easily, so a plant preparation that breaks biofilms would be valuable. The head-to-head design respects folk practice while holding it to laboratory standards.
Catalog record
| CREATOR | Yasir Almuhanna, Mohammed Asad, Mohammed S. Alshammari, Babu Joseph |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |