The Role of Regulatory B Lymphocytes in Allergic Diseases
Agnieszka Lipińska-Opałka, Michalina Leszczyńska-Pilich, Agata Będzichowska, Agata Tomaszewska, Agnieszka Rustecka, Bolesław Kalicki, Carmen Panaitescu · 2024
Read The Role of Regulatory B Lymphocytes in Allergic Diseases by Agnieszka Lipińska-Opałka, Michalina Leszczyńska-Pilich, Agata Będzichowska, Agata Tomaszewska, Agnieszka Rustecka, Bolesław Kalicki, Carmen Panaitescu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11726865.txt.
Description
Most B cells help fight germs, but a quiet subset, regulatory B cells, calms the immune system down. Agnieszka Lipińska-Opałka and co-authors reviewed what those cells do in allergic diseases in 2024, and why allergy patients seem to have too few of them.
The cells mainly work by releasing a soothing signal, IL-10, and by direct contact with other immune cells. In asthma, eczema, and food allergy, their numbers drop, and the fewer cells a patient has, the worse the disease tends to be. Eczema patients' cells also answer stimulation weakly. Allergy shots, though, can grow these cells back. The review says future cell therapies hinge on pinning down what marks a regulatory B cell.
Catalog record
| CREATOR | Agnieszka Lipińska-Opałka, Michalina Leszczyńska-Pilich, Agata Będzichowska, Agata Tomaszewska, Agnieszka Rustecka, Bolesław Kalicki, Carmen Panaitescu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |