Predictors of Successful Testicular Sperm Extraction: A New Era for Men with Non-Obstructive Azoospermia
Aris Kaltsas, Sofoklis Stavros, Zisis Kratiras, Athanasios Zikopoulos, Nikolaos Machairiotis, Anastasios Potiris, Fotios Dimitriadis, Nikolaos Sofikitis, Michael Chrisofos, Athanasios Zachariou, Bo-Ying Bao · 2024
Read Predictors of Successful Testicular Sperm Extraction: A New Era for Men with Non-Obstructive Azoospermia by Aris Kaltsas, Sofoklis Stavros, Zisis Kratiras, Athanasios Zikopoulos, Nikolaos Machairiotis, Anastasios Potiris, Fotios Dimitriadis, Nikolaos Sofikitis, Michael Chrisofos, Athanasios Zachariou, Bo-Ying Bao (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11726830.txt.
Description
Aris Kaltsas and co-authors review the hunt for a reliable forecast of sperm retrieval in men whose testes fail to release sperm. In non-obstructive azoospermia, surgery combined with injection of a single sperm into an egg is the only route to fatherhood, yet success is a coin flip that costs money and hope. The review grades old predictors and new ones.
Age, body mass, testicular volume, and standard hormones all predict weakly. Better promise comes from anti-Müllerian hormone ratios, small regulatory RNAs, and sperm-lineage proteins like TEX101, plus high-frequency ultrasound and functional MRI. The authors see the future in combining molecular markers with machine learning, while warning that most candidates still await solid validation before clinics can lean on them.
Catalog record
| CREATOR | Aris Kaltsas, Sofoklis Stavros, Zisis Kratiras, Athanasios Zikopoulos, Nikolaos Machairiotis, Anastasios Potiris, Fotios Dimitriadis, Nikolaos Sofikitis, Michael Chrisofos, Athanasios Zachariou, Bo-Ying Bao |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |