Decoding FGF/FGFR Signaling: Insights into Biological Functions and Disease Relevance

Oshadi Edirisinghe, Gaëtane Ternier, Zeina Alraawi, Thallapuranam Krishnaswamy Suresh Kumar, Ryan Moseley · 2024

Read Decoding FGF/FGFR Signaling: Insights into Biological Functions and Disease Relevance by Oshadi Edirisinghe, Gaëtane Ternier, Zeina Alraawi, Thallapuranam Krishnaswamy Suresh Kumar, Ryan Moseley (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11726770.txt.

Description

Oshadi Edirisinghe and co-authors published a review in twenty twenty-four decoding the signaling system of fibroblast growth factors and their receptors. These signals steer cell growth, specialization, tissue repair, and metabolic balance throughout life. The same pathways, when mis-set, feed many diseases.

The review lays out how the signals are built, switched, and cross-connected with other signaling networks. It also surveys the family's roles in development and everyday housekeeping in the body. By gathering current and emerging research in one map, the authors aim to help readers see where medicines could intervene. They argue that mastering this system is crucial for treating growth-factor-driven disorders.

Catalog record

CREATOROshadi Edirisinghe, Gaëtane Ternier, Zeina Alraawi, Thallapuranam Krishnaswamy Suresh Kumar, Ryan Moseley
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE77 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11726770

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