Association of IDH1 Mutation and MGMT Promoter Methylation with Clinicopathological Parameters in an Ethnically Diverse Population of Adults with Gliomas in England
Hiba A Wanis, Henrik Møller, Keyoumars Ashkan, Elizabeth A Davies, Dimitrios Kanakis · 2024
Read Association of IDH1 Mutation and MGMT Promoter Methylation with Clinicopathological Parameters in an Ethnically Diverse Population of Adults with Gliomas in England by Hiba A Wanis, Henrik Møller, Keyoumars Ashkan, Elizabeth A Davies, Dimitrios Kanakis (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11726743.txt.
Description
Hiba Wanis and co-authors profiled brain tumors across a diverse region in two thousand twenty-four. The tumors, called gliomas, vary in gene traits that guide care. Two traits matter most: a gene change and a gene silencing mark. The study covered adults treated in southeast London and Kent. That area holds about three million people of many backgrounds.
Hospital records covered more than seven hundred patients. Cases spanned five years of diagnoses. The team linked gene traits to age, sex, and ethnic background. Tumor type, site, and surgery extent were also factored in. Rates of each trait were compared across groups. Such profiles help labs plan testing for all patients fairly. They also reveal whether access to new targeted drugs is even.
Catalog record
| CREATOR | Hiba A Wanis, Henrik Møller, Keyoumars Ashkan, Elizabeth A Davies, Dimitrios Kanakis |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |