Differential expression of ABO in normal and tumor tissues: Implications for cancer biology and prognosis
Hind M. Albadrani, Munerah Hamed, Abeer Zakariyah, Samar Binkheder, Saeed M. Kabrah, Arwa F. Flemban · 2024
Read Differential expression of ABO in normal and tumor tissues: Implications for cancer biology and prognosis by Hind M. Albadrani, Munerah Hamed, Abeer Zakariyah, Samar Binkheder, Saeed M. Kabrah, Arwa F. Flemban (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11720615.txt.
Description
Hind Albadrani and co-authors chart where the blood-group gene ABO is switched on, in healthy tissue and in tumors. Their 2024 study uses a public cancer expression database to compare the gene's activity across many tissue and cancer types. ABO decides blood type, but its wider tissue pattern hints at roles in cancer growth and survival.
Ovary and thyroid tissues showed the highest activity, while liver, thymus, and brain sat low. Tumor levels differed from their matching healthy tissues in several cancers, and the authors test links to patient survival. The survey sizes up ABO as a possible prognostic sign beyond the blood bank.
Catalog record
| CREATOR | Hind M. Albadrani, Munerah Hamed, Abeer Zakariyah, Samar Binkheder, Saeed M. Kabrah, Arwa F. Flemban |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |